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Year 1

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  1. Brubaker DK, Paulo JA, Sheth S, Poulin EJ, Popow O, Joughin BA, ... Haigis KM. (2019). Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation. Cell systems, 9(3), pp. 258-270.e6. doi: 10.1016/j.cels.2019.07.006

  2. Haigis KM, Cichowski K, Elledge SJ. (2019). Tissue-specificity in cancer: The rule, not the exception. Science (New York, N.Y.), 363(6432), pp. 1150-1151. doi: 10.1126/science.aaw3472

  3. Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, ... Haigis KM. (2019). Tissue-Specific Oncogenic Activity of KRAS. Cancer discovery, 9(6), pp. 738-755. doi: 10.1158/2159-8290.CD-18-1220

  4. Gay DM, Ridgway RA, Müller M, Hodder MC, Hedley A, Clark W, ... Sansom OJ. (2019). Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer. Nature communications, 10(1), pp. 723. doi: 10.1038/s41467-019-08586-3Geurts MH, de Poel E,

 

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Year 2

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  1. Bianchi JJ, Zhao X, Mays JC, Davoli T. (2020). Not all cancers are created equal: Tissue specificity in cancer genes and pathways. Current opinion in cell biology, 63, pp. 135-143. doi: 10.1016/j.ceb.2020.01.005

  2. Amatngalim GD, Oka R, Meijers FM, Kruisselbrink E, ... Clevers H. (2020). CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank. Cell stem cell, 26(4), pp. 503-510.e7. doi: 10.1016/j.stem.2020.01.019

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Year 3

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1. Flanagan DJ, Pentinmikko N, Luopajärvi K, Willis NJ, Gilroy K, Raven AP, Mcgarry L, Englund JI, Webb AT, Scharaw S, Nasreddin N, Hodder MC, Ridgway RA, Minnee E, Sphyris N, Gilchrist E, Najumudeen AK, Romagnolo B, Perret C, Williams AC, Clevers H, Nummela P, Lähde M, Alitalo K, Hietakangas V, Hedley A, Clark W, Nixon C, Kirschner K, Jones EY, Ristimäki A, Leedham SJ, Fish PV, Vincent JP, Katajisto P, Sansom OJ. (2021) NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature, 594(7863), pp. 430-435. doi: 10.1038/s41586-021-03525-z. 

2. Leach JDG, Vlahov N, Tsantoulis P, Ridgway RA, Flanagan DJ, Gilroy K, Sphyris N, Vázquez EG, Vincent DF, Faller WJ, Hodder MC, Raven A, Fey S, Najumudeen AK, Strathdee D, Nixon C, Hughes M, Clark W, Shaw R; S:CORT consortium, van Hooff SR, Huels DJ, Medema JP, Barry ST, Frame MC, Unciti-Broceta A, Leedham SJ, Inman GJ, Jackstadt R, Thompson BJ, Campbell AD, Tejpar S, Sansom OJ (2021). Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis. Nature communiations, 12(1), pp. 3464. doi: 10.1038/s41467-021-23717-5.

3. William W.#, Zhao X., Bianchi J.,  Lin H.,  Cheng P.,  Lee J.,  Carter H. , Alexandrov L., Spetzler D. B., Dubinett S.M., Cleveland D., Cavenee W.,  Davoli T.# , Lippman S. (2021) Immune evasion in HPV-negative head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss. #corresponding authors PNAS, 118 (19), e2022655118.

4. Geurts MH, de Poel E, Pleguezuelos-Manzano C, Oka R, Carrillo L, Andersson-Rolf A, Boretto M, Brunsveld JE, van Boxtel R, Beekman JM, Clevers H (2021). Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids. Life Science Alliance, 4(10), e202000940. doi: 10.26508/lsa.202000940.

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